Mechanism of host substrate acetylation by a YopJ family effector
نویسندگان
چکیده
منابع مشابه
Acetylation of MEK2 and I B kinase (IKK) activation loop residues by YopJ inhibits signaling
To overcome host defenses, bacterial pathogens of the genus Yersinia inject specific effector proteins into colonized mammalian cells. One such virulence factor, YopJ, inhibits the host inflammatory response and induces apoptosis of immune cells by blocking multiple signaling pathways, including the MAPK and NFB pathways. In this study, we show that YopJ exerts its deleterious effects by cataly...
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ژورنال
عنوان ژورنال: Nature Plants
سال: 2017
ISSN: 2055-0278
DOI: 10.1038/nplants.2017.115